Commercialisation news

The latest commercialisation news from the ±¬ÁÏTV.

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batteries

Northern Gritstone co-leads £2 million pre-seed round into AmpliSi

AmpliSi, a ±¬ÁÏTV spinout developing silicon anodes for next-generation lithium-ion batteries, has secured a £2 million pre-seed investment led by Northern Gritstone and Clean Growth Fund. 
A large powerline at sunset

New AI software set to accelerate delivery of vital Net-Zero infrastructure

New software, developed by the ±¬ÁÏTV spin-out AENi and funded by the Grantham Centre for Sustainable Futures, aims to transform how the world’s essential net-zero infrastructure is planned.
Professor Sheila MacNeil

Advancing safer treatments in women’s pelvic health

Stress urinary incontinence affects up to one in three women worldwide, but the most commonly used treatment has led to serious problems. Sheffield spinout, Audaxis Medical, is developing a new medical device that could be a safer option.

Group of people talking at an event

Highlights and achievements from the 2025 Commercialisation Journey

Celebrating the standout moments from this year’s Commercialisation Journey.
Computer symbols of people are connected in a network.

Spinout spotlight: Kausalyze

Kausalyze, a spinout from the ±¬ÁÏTV's School of Chemical, Materials and Biological Engineering, is providing systems-level intelligence to help process manufacturers reduce downtime and increase operational efficiency.
Heather Mortiboys in a lab coat looks up from microscope

Spinout spotlight: Mitotype Precision Labs

Mitotype Precision Labs (MPL) is transforming how we screen drugs for neurodegenerative diseases. Their novel platform identifies treatments capable of restoring mitochondrial function, paving the way for disease-modifying therapies.
SilViA Bio

Spinout spotlight: SilViA Bio

SilViA Bio, a biotechnology spinout from the ±¬ÁÏTV's School of Chemical, Materials and Biological Engineering, is helping to make biomanufacturing faster, cheaper, and more reliable.

Dr Rob Ward presenting at Trade Mission

Sheffield spinouts take centre stage at London Stock Exchange Trade Mission

The recent Trade Mission to the London Stock Exchange provided an opportunity to showcase the region's fast-growing digital and advanced manufacturing sectors, as well as the talented startup businesses that have spun out from the University.
Electric signals

Crucible Therapeutics appoints new Chief Executive Officer

Crucible Therapeutics, a ±¬ÁÏTV spinout developing novel therapies for amyotrophic lateral sclerosis (ALS) and other neurodegenerative diseases, has announced the appointment of Dr Cliff Holloway as its Chief Executive Officer.
Sheffield Business Awards 2025 winners

Triple triumph: Sheffield spinouts shine at 2025 Business Awards

Two spinout companies from the University's School of Electrical and Electronic Engineering achieved a triple triumph at this year's Sheffield Business awards, collectively taking home three awards.
Two people shaking hands

AMRC FerretWorks programme: Turning bold ideas into breakthrough innovations

The AMRC FerretWorks: Startup programme is supporting early-stage entrepreneurs in the South Yorkshire region by bringing the centre's world-class resources to those with bold ideas and the ambition to scale.
Three people networking at the Innovation Sprint event

The Northern Triangle Talent Project: One year on

The Northern Triangle Talent (NTT) project, a collaboration between Sheffield, Leeds, and Manchester universities, is powering northern spinouts by building a strong, globally-focused mentor community.
Doctor audiologist using otoscope while examining ear of his senior adult patient in doctor's office

First-in-human trial for regenerative cell therapy for sensorineural hearing loss approved 

Rinri Therapeutics, a world leading spinout company from the ±¬ÁÏTV dedicated to transforming sensorineural hearing loss (SNHL) with regenerative cell therapy, has received approval to begin its first-in-human clinical trial. 
Brain-inspired neuromorphic computing

AI-driven spinout set to transform advanced manufacturing

Yorkshire AI Labs, in partnership with Dr Rob Ward and the ±¬ÁÏTV’s Advanced Manufacturing Research Centre (AMRC), has launched DigitalCNC, an AI-driven precision manufacturing software company.
Sheffield city centre at night time

University Spinouts: The Sheffield Difference

Sheffield is creating a strong future for University spinouts. With our growing investor network, improving infrastructure and rich talent pool, we are laying the foundations for the next generation of research-driven innovators to thrive.
Electric signals

Crucible Therapeutics awarded £2.3 million to develop breakthrough therapies that address underlying causes of MND

Crucible Therapeutics, a biotechnology spinout company, and ±¬ÁÏTV secure a £2.3 million Innovate UK Biomedical Catalyst award to develop breakthrough siRNA therapies that address underlying causes of Motor Neuron Disease (MND).
Geoptic logo

Geoptic awarded prestigious King’s Award for Enterprise in Innovation

Geoptic has been awarded a King’s Award for Enterprise in the Innovation category — considered the highest official honours for UK businesses.

DNA strand

FDA approves trial to advance pioneering treatment for Hereditary Spastic Paraplegia (HSP)

The US Food and Drug Administation (FDA) has approved BlackfinBio Limited’s Phase 1/2 clinical trial for its novel adeno-associated virus (AAV) gene therapy targeting Hereditary Spastic Paraplegia (HSP) Type 47 (SPG47).
Researcher working in AMRC facility

Leading investors back Northern Gritstone with new £50 million fundraise

Northern Gritstone has announced its latest fundraise of £50 million from leading institutional investors bringing its total permanent capital to £362 million.

DNA strands

Sheffield spinout takes major step towards advancing pioneering treatments for Hereditary Spastic Paraplegia (HSP)

BlackfinBio Limited is a spinout company from the ±¬ÁÏTV set to pioneer novel therapies for rare genetic neurological diseases.

Exciting Instruments team

±¬ÁÏTV spinout secures £4m in seed funding round - technology set to support health-related research

A ±¬ÁÏTV spinout that has developed a single-molecule detection platform to support health research has raised £4m in funding.
Laboratory technician uses micro-pipette

City centre labs to drive innovation and start-up success

In a move set to propel innovation and growth of early-stage companies, Sheffield Technology Parks (STP) and ±¬ÁÏTV are teaming up to build new lab spaces in the city centre.

An image of the Tasty Spoon concept, an arm of a woman is holding the spoon above a plate. The spoon is grey.

New ‘Tasty Spoon’™ will enhance food flavours for people living with dementia

A spoon, designed to enhance the flavour of food for dementia patients experiencing a loss of taste, could help combat high levels of malnutrition.
Group of people talking at an event

Northern universities launch spinout mentor network to empower entrepreneurs

The universities of Sheffield, Leeds, and Manchester are proud to announce the launch of the Northern Triangle Mentor Network, a dynamic initiative designed to propel commercialisation opportunities and empower early-stage spinouts.
Medical illustration of a brain with stroke symptoms

New company Midland Pharmaceuticals launched to develop therapeutics for stroke and spinal cord injury

Researchers from the ±¬ÁÏTV and the University of Birmingham have joined forces with NLC Health Ventures to co-found a company developing new treatments for spinal cord injuries and stroke.
DNA Molecule

Sheffield spinout company grows to lead on next generation biomedicines and bioprocesses

SynGenSys, a fast-growing biotechnology company spun out of the ±¬ÁÏTV, has announced the appointment of Dr. Andy Racher as its Commercial Operations Director.
A portrait photo of Professor James Marshall

World leading expert on bio-inspired AI to direct ±¬ÁÏTV’s Centre for Machine Intelligence

One of the world’s leading innovators in bio-inspired AI has joined the ±¬ÁÏTV, as part of a new multi-million pound centre that is set to transform the institution’s research, innovation and teaching around artificial intelligence.

Dr Tim Craggs with instrument

Northern Triangle Talent Project secures £1.5m funding to strengthen regional commercialisation activity

The Northern Triangle Talent Project has secured funding to strengthen the regional technology commercialisation ecosystem and attract top talent to the north of England.
DNA Molecule

±¬ÁÏTV spinout company to pioneer novel therapies for genetic neurological diseases

BlackfinBio has raised £2.75 million seed investment to advance revolutionary treatments for Hereditary Spastic Paraplegia (HSP).

A close up of plastic pellets produced by Floreon

World’s first low-energy bioplastics developed with the ±¬ÁÏTV raises £2 million investment

The world’s first low-energy, non-oil-based, high-performance bioplastic, developed by Floreon with the ±¬ÁÏTV, has secured £2 million financing from Northern Gritstone.

Neuron cells system - 3d rendered image of Neuron cell network on black background

±¬ÁÏTV spinout company Crucible Therapeutics raises £5 million to advance pioneering treatments for neurological diseases

±¬ÁÏTV spinout company, Crucible Therapeutics, a biotechnology company developing novel therapies to treat the most common genetic form of MND and frontotemporal dementia (FTD), has secured £5 million from Northern Gritstone.
An aerial view of the ±¬ÁÏTV Innovation District featuring the Factory 2050 building

Investment zones are the key to taking our potential towards prosperity

Professor Koen Lamberts, President and Vice-Chancellor of the ±¬ÁÏTV, discusses how the new South Yorkshire Investment Zone can turn Yorkshire's potential into prosperity.

Inner ear

Unlocking the human inner ear for new therapies to improve hearing loss and deafness

An international team of scientists and surgeon has discovered a secure clinical pathway to the inner ear, which will enable the application of a range of regenerative therapies to restore hearing.

A blue sky above the University's Diamond building

Northern Gritstone secures first close of £215 million ahead of making its first investments

A new investment company founded by the universities of Sheffield, Leeds and Manchester to help boost the commercialisation of university spinouts and start-ups in the north of England has today (20 May 2022) announced a first close of £215 million.
Close up of ear

Rinri Therapeutics raises £10 million to advance stem cell therapy for hearing loss

±¬ÁÏTV spinout company, Rinri Therapeutics, has raised a total of £10 million from investors and the UK Future Fund to advance its novel stem cell therapy to restore hearing loss.

Abstract woman scientist illustration

Sheffield spin-out set up to facilitate life-science discoveries

Understanding how molecules interact within the body is essential in supporting the development of treatments and therapies. Exciting Instruments, a ±¬ÁÏTV spin-out company, is breaking down barriers for researchers in this field.
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Northern Gritstone announces leadership team

Northern Gritstone, a new investment company founded by the Universities of Leeds, Manchester and Sheffield, has appointed Lord Jim O’Neill as Non-Executive Chairman and Duncan Johnson as CEO.
Universities of Sheffield, Leeds and Manchester launch Northern Gritstone

Northern universities launch new investment company

The universities of Sheffield, Leeds and Manchester are launching a new investment company to help boost the commercialisation of university spinouts and start-ups in the North of England.