Dr Tobias Moll

PhD

School of Medicine and Population Health

MND Association Lady Edith Wolfson Research Fellow

Tobias Moll
Profile picture of Tobias Moll
tobias.moll@sheffield.ac.uk
B27, Sheffield Institute for Translational Neuroscience (SITraN)

Full contact details

Dr Tobias Moll
School of Medicine and Population Health
B27
Sheffield Institute for Translational Neuroscience (SITraN)
385a Glossop Road
Sheffield
S10 2HQ
Profile

I was awarded my PhD from the TV in 2020 for my thesis describing novel genetic drivers of amyotrophic lateral sclerosis (ALS), conducted under the supervision of Professor Dame Pamela Shaw and Dr. Johnathan Cooper-Knock. I undertook postdoctoral training in the same lab to build upon my PhD research which included a period of study in California, USA. I was then awarded a Lady Edith Wolfson MND Association Fellowship in 2024 to investigate disruption of membrane lipid raft homeostasis and localised neurotrophin signalling impairments in ALS. 

Publications

Journal articles

  • Demaegd KC, Kernan A, Cooper-Knock J, van Vugt JJFA, Harvey C, Moll T, O’Brien D, Gornall S, Drury L, Farhan SMK , Dion PA et al (2025) . European Journal of Human Genetics, 33(9), 1106-1112.
  • Harvey C, Nowak A, Zhang S, Moll T, Weimer AK, Barcons AM, Souza CDS, Ferraiuolo L, Kenna K, Zaitlen N , Caggiano C et al (2025) . BMC Medical Genomics, 18.
  • Huang W-P, Ellis BCS, Hodgson RE, Sanchez Avila A, Kumar V, Rayment J, Moll T & Shelkovnikova TA (2024) . Cell Reports, 43(7).
  • (2024) , 75-86.
  • Harvey C, Weinreich M, Lee JAK, Shaw AC, Ferraiuolo L, Mortiboys H, Zhang S, Hop PJ, Zwamborn RAJ, van Eijk K , Julian TH et al (2024) . Heliyon, 10(3).
  • Moll T, Odon V, Harvey C, Collins MO, Peden A, Franklin J, Graves E, Marshall JNG, dos Santos Souza C, Zhang S , Castelli L et al (2023) . Life Science Alliance, 6(1).
  • Cooper‐Knock J, Julian TH, Feneberg E, Highley JR, Sidra M, Turner MR, Talbot K, Ansorge O, Allen SP, Moll T , Shelkovnikova T et al (2023) . Brain Pathology, 33(1).
  • Franklin J, Cooper-Knock J, Baheerathan A, Moll T, Heverin M, Hardiman O, Mannikko R, Shaw P & Hanna M (2022) . Journal of Neurology, Neurosurgery & Psychiatry, 93(6), A13-A13.
  • Boddy S, Islam M, Moll T, Kurz J, Burrows D, McGown A, Bhargava A, Julian TH, Harvey C, Marshall JNG , Hall BPC et al (2022) . Brain Communications, 4(2).
  • Zhang S, Cooper-Knock J, Weimer AK, Shi M, Moll T, Marshall JNG, Harvey C, Nezhad HG, Franklin J, Souza CDS , Ning K et al (2022) . Neuron, 110(6), 992-1008.
  • Julian TH, Boddy S, Islam M, Kurz J, Whittaker KJ, Moll T, Harvey C, Zhang S, Snyder MP, McDermott C , Cooper-Knock J et al (2022) . Brain, 145(3), 832-842.
  • Moll T, Marshall JNG, Soni N, Zhang S, Cooper-Knock J & Shaw PJ (2021) . Essays in Biochemistry, 65(7), 999-1011.
  • Cooper-Knock J, Harvey C, Zhang S, Moll T, Timpanaro IS, Kenna KP, Iacoangeli A & Veldink JH (2021) . Current Opinion in Neurology, 34(5), 756-764.
  • Julian TH, Glascow N, Barry ADF, Moll T, Harvey C, Klimentidis YC, Newell M, Zhang S, Snyder MP, Cooper-Knock J & Shaw PJ (2021) . EBioMedicine, 68.
  • Cooper-Knock J, Zhang S, Kenna KP, Moll T, Franklin JP, Allen S, Nezhad HG, Iacoangeli A, Yacovzada NY, Eitan C , Hornstein E et al (2021) . Cell Rep, 34(5), 108730.
  • Ghahremani Nezhad H, Franklin JP, Alix JJP, Moll T, Pattrick M, Cooper-Knock J, Shanmugarajah P, Beauchamp NJ, Hadjivissiliou M, Paling D , Mcdermott C et al (2020) . Amyotrophic Lateral Sclerosis and Frontotemporal Degeneration, 22(7-8), 579-582.
  • Cooper-Knock J, Zhang S, Kenna KP, Moll T, Franklin JP, Allen S, Nezhad HG, Iacoangeli A, Yacovzada NY, Eitan C , Hornstein E et al (2020) . Cell Reports, 33(9).
  • Shabir O, Moll TA, Matuszyk MM, Eyre B, Dake MD, Berwick J & Francis SE (2020) . Mechanisms of Ageing and Development, 192, 111361-111361.
  • Franklin JP, Cooper-Knock J, Baheerathan A, Moll T, Männikkö R, Heverin M, Hardiman O, Shaw PJ & Hanna MG (2020) . Amyotrophic Lateral Sclerosis and Frontotemporal Degeneration, 21(7-8), 627-630.
  • Moll T, Shaw PJ & Cooper-Knock J (2020) . Brain, 143(5), 1332-1340.
  • Cooper-Knock J, Moll T, Ramesh T, Castelli L, Beer A, Robins H, Fox I, Niedermoser I, Van Damme P, Moisse M , Robberecht W et al (2019) . Cell Reports, 26(9), 2298-2306.e5.
  • Alhathli E, Cooper-Knock J, Girach Z-U-A, Julian TH, Bauer C, Timmons HO, Ward BD, Walker H, Azzouz M, Elrayess MA , Al-Khelaifi F et al () . BMC Medicine.

Conference proceedings

  • Cooper-Knock J, Moll T, Ramesh T, Castelli L, Shaw C, Al-Chalabi A, McDermott C, Hautbergue G & Shaw P (2019) . Journal of Neurology, Neurosurgery & Psychiatry, Vol. 90(12) (pp e10.3-e11)
  • Cooper-Knock J, Moll T, Ramesh T, Castelli L, Shaw C, Al-Chalabi A, McDermott C, Hautbergue G & Shaw P (2019) MUTATIONS IN THE GLYCOSYLTRANSFERASE DOMAIN OF GLT8D1 CAUSE ALS. JOURNAL OF NEUROLOGY NEUROSURGERY AND PSYCHIATRY, Vol. 90(12) (pp E20-E21)

Preprints

  • Alhathli E, Girach Z-U-A, Julian T, Bauer C, Azzouz M, Elrayess MA, Al-Khelaifi F, Yousri NA, Gul A, Kelsall A , Moll T et al (2025) , Springer Science and Business Media LLC.
  • Cooper-Knock J, Demaegd K, Kernan A, Vugt JV, Harvey C, Moll T, O'Brien D, Gornall S, Drury L, Farhan S , Dion P et al (2024) , Springer Science and Business Media LLC.
  • Zhang S, Moll T, Rubin-Sigler J, Tu S, Li S, Yuan E, Liu M, King M, Alhalthli E, Treanor C , Twelvetrees A et al (2024) , openRxiv.
  • Moll T, Graves E, Urbanek A, Soni N, Ranganathan R, Higginbottom A, Wang S, Head BP, Cooper-Knock J & Shaw PJ (2022) , Cold Spring Harbor Laboratory.
  • Harvey C, Weinreich M, Zhang S, Hop PJ, Zwamborn RAJ, van Eijk K, Julian TH, Moll T, Iacoangeli A, Khleifat AA , Quinn JP et al (2022) , openRxiv.
  • Moll T, Odon V, Harvey C, Collins MO, Peden A, Franklin J, Graves E, Marshall JNG, Santos Souza CD, Zhang S , Azzouz M et al (2022) , Cold Spring Harbor Laboratory.
  • Zhang S, Cooper-Knock J, Weimer AK, Shi M, Moll T, Harvey C, Nezhad HG, Franklin J, dos Santos Souza C, Wang C , Li J et al (2020) , Cold Spring Harbor Laboratory.
  • Julian TH, Glascow N, Fisher Barry AD, Moll T, Harvey C, Klimentidis YC, Newell M, Zhang S, Snyder MP, Cooper-Knock J & Shaw PJ () .
  • Zhang S, Cooper-Knock J, Weimer AK, Shi M, Moll T, Harvey C, Nezhad HG, Franklin J, Souza CDS, Wang C , Li J et al () .
  • Cooper-Knock J, Zhang S, Kenna KP, Moll T, Franklin J, Allen S, Nezhad HG, Yacovzada NS, Eitan C, Hornstein E , Ehilak E et al () .
  • Cooper-Knock J, Moll T, Ramesh T, Castelli L, Beer A, Robins H, Fox I, Niedermoser I, Van Damme P, Robberecht W , Hardiman O et al () .
Research group
  • Connie Treanor (PhD student)
  • Akanksha Jangid (Research Assistant)