Dr Lisa Parker

BSc, MRes, PhD, PGCert, FHEA

School of Medicine and Population Health

Lecturer in Inflammation Biology

l.c.parker@sheffield.ac.uk
+44 114 215 9544
The Medical School

Full contact details

Dr Lisa Parker
School of Medicine and Population Health
The Medical School
Beech Hill Road
Sheffield
S10 2RX
Profile

I graduated from the University of Manchester in 1996 with a BSc (First Class Honours) in Neuroscience. I then completed an MRes in Neuroscience (University of Manchester, 1997) followed by my PhD entitled `Interleukin-1 and its receptors in the brain´ under the supervision of Professor Dame Nancy Rothwell (University of Manchester, 1997-2000).

I joined the ±¬ÁÏTV in 2001 to take up my first post-doctoral position, where I was keen to maintain and develop my interest into inflammatory mechanisms in disease, with a focus on the respiratory system. In 2010 I was appointed to a lectureship within the Inflammation Biology Research Group and in 2014 I was awarded the Postgraduate Certificate in Learning and Teaching (PG CiLT) and became a Fellow of The Higher Education Academy (FHEA). 

During my lectureship my increasing involvement in teaching ignited a strong passion for learning and teaching, prompting me to actively pursue opportunities that would allow me to focus more on educational roles. In 2010 I started to teach on the MSc Molecular Medicine degree, this developed into running several modules for the course and I was appointed Deputy Programme Lead in 2023. During this time I also designed and led modules for several other courses, at both postgraduate and undergraduate level. I currently teach on multiple programmes within the School of Medicine and Population Health, and the School of Biosciences. 

In the last few years I have also taken on multiple teaching-focused leadership roles. I was appointed Deputy Director of Phase 1 (MBChB) in 2021, and I also lead the MBChB Phase 2a Immunology block. My involvement with the MBChB has continued to develop, I was appointed Associate Director of Student Affairs (MBChB) in 2024 and Deputy Programme Lead of BSc in Medical Sciences Research Intercalation studies in 2025. 

I am also a Faculty of Health representative for the Learning and Teaching Scholarship Network (LTSN) Steering committee, SMPH Annual Research Meeting Working Group committee member and SMPH Athena Swan Committee member.

Qualifications

Academic

  • 2000: PhD, Division of Neuroscience, University of Manchester Professor Dame Nancy Rothwell & Dr Giamal Luheshi
  • 1997: MRes, Division of Neuroscience, University of Manchester
  • 1996: BSc (Hons) First Class, Neuroscience, University of Manchester

Professional

  • 2014: Postgraduate Certificate in Learning and Teaching (PGCert Learning and Teaching), ±¬ÁÏTV
  • 2014: Fellow of the Higher Education Academy (FHEA)
Publications

Show: Featured publications All publications

Journal articles

  • Bradley KL, Stokes CA, Marciniak SJ, Parker LC & Condliffe AM (2021) . Thorax, 76(1), 92-99.
  • Marsh EK, Prestwich EC, Williams L, Hart AR, Muir CF, Parker LC, Jonker MR, Heijink IH, Timens W, Fife M , Hussell T et al (2020) . Frontiers in Cellular and Infection Microbiology, 10.
  • Mills JT, Schwenzer A, Marsh EK, Edwards MR, Sabroe I, Midwood KS & Parker LC (2019) . Frontiers in Immunology, 10.
  • Manley GCA, Stokes CA, Marsh EK, Sabroe I & Parker LC (2019) . Journal of Virology, 93(2).
  • Stokes CA, Kaur R, Edwards MR, Mondhe M, Robinson D, Prestwich EC, Hume RD, Marshall CA, Perrie Y, O'Donnell VB , Harwood JL et al (2016) . Mucosal Immunology, 9(5), 1303-1316.
  • Ismail S, Stokes CA, Prestwich EC, Roberts RL, Juss JK, Sabroe I & Parker LC (2014) . PLoS One, 9(12).
  • Parker LC, Stokes CA & Sabroe I (2014) . Clin Exp Allergy, 44(1), 20-28.
  • Bennett JA, Prince LR, Parker LC, Stokes CA, de Bruin HG, van den Berge M, Heijink IH, Whyte MK & Sabroe I (2012) . J Virol, 86(12), 6595-6604.
  • Stokes CA, Ismail S, Dick EP, Bennett JA, Johnston SL, Edwards MR, Sabroe I & Parker LC (2011) . J Virol, 85(15), 7912-7921.
  • Parker LC, Prestwich EC, Ward JR, Smythe E, Berry A, Triantafilou M, Triantafilou K & Sabroe I (2008) . J Immunol, 181(8), 5606-5617.

All publications

Journal articles

  • Bradley KL, Stokes CA, Marciniak SJ, Parker LC & Condliffe AM (2021) . Thorax, 76(1), 92-99.
  • Marsh EK, Prestwich EC, Williams L, Hart AR, Muir CF, Parker LC, Jonker MR, Heijink IH, Timens W, Fife M , Hussell T et al (2020) . Frontiers in Cellular and Infection Microbiology, 10.
  • Mills JT, Schwenzer A, Marsh EK, Edwards MR, Sabroe I, Midwood KS & Parker LC (2019) . Frontiers in Immunology, 10.
  • Manley GCA, Parker LC & Zhang Y (2019) . International Journal of Molecular Sciences, 20(3).
  • Manley GCA, Stokes CA, Marsh EK, Sabroe I & Parker LC (2019) . Journal of Virology, 93(2).
  • Stokes C, Kaur R, Edwards MR, Mohdhe M, Robinson D, Prestwich EC, Hume RD, Marshall CA, Perrie Y, O'Donnell VB , Harwood JL et al (2017) . Mucosal Immunology, 10.
  • Stokes CA, Kaur R, Edwards MR, Mondhe M, Robinson D, Prestwich EC, Hume RD, Marshall CA, Perrie Y, O'Donnell VB , Harwood JL et al (2016) . Mucosal Immunology, 9(5), 1303-1316.
  • Ismail S, Stokes CA, Prestwich EC, Roberts RL, Juss JK, Sabroe I & Parker LC (2014) . PLoS One, 9(12).
  • Parker LC, Stokes CA & Sabroe I (2014) . Clin Exp Allergy, 44(1), 20-28.
  • Sabroe RA, Stokes CA, Parker LC, Higgins K, Prince LR & Sabroe I (2013) . Clinical and Experimental Dermatology.
  • Piper SC, Ferguson J, Kay L, Parker LC, Sabroe I, Sleeman MA, Briend E & Finch DK (2013) . PLoS One, 8(5), e63365.
  • Basran A, Jabeen M, Bingle L, Stokes CA, Dockrell DH, Whyte MKB, Walmsley SR, Higgins KR, Vogel SN, Wilson HL , Prince LR et al (2013) . J Leukoc Biol, 93(1), 7-19.
  • Chaudhuri N, Jary H, Lea S, Khan N, Piddock KC, Dockrell DH, Donaldson K, Duffin R, Singh D, Parker LC & Sabroe I (2012) . PLoS One, 7(12), e51107.
  • Bennett JA, Prince LR, Parker LC, Stokes CA, de Bruin HG, van den Berge M, Heijink IH, Whyte MK & Sabroe I (2012) . J Virol, 86(12), 6595-6604.
  • Prince LR, Whyte MK, Sabroe I & Parker LC (2011) . CURR OPIN PHARMACOL, 11(4), 397-403.
  • Stokes CA, Ismail S, Dick EP, Bennett JA, Johnston SL, Edwards MR, Sabroe I & Parker LC (2011) . J Virol, 85(15), 7912-7921.
  • Walmsley SR, Chilvers ER, Thompson AA, Vaughan K, Marriott HM, Parker LC, Shaw G, Parmar S, Schneider M, Sabroe I , Dockrell DH et al (2011) . J Clin Invest, 121(3), 1053-1063.
  • Ward JR, West PW, Ariaans MP, Parker LC, Francis SE, Crossman DC, Sabroe I & Wilson HL (2010) . J Biol Chem, 285(30), 23147-23158.
  • Chaudhuri N, Piddock K, Donaldson K, Parker L & Sabroe I (2010) Diesel Exhaust Particles Alter Monocyte Differentiation In Vitro. AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE, 181.
  • Chaudhuri N, Paiva C, Donaldson K, Duffin R, Parker LC & Sabroe I (2010) . Am J Physiol Lung Cell Mol Physiol, 299(2), L263-L271.
  • Parker LC, Prince LR, Buttle DJ & Sabroe I (2009) . Methods Mol Biol, 517, 191-204.
  • Chaudhuri N, Donaldson K, Parker LC & Sabroe I (2009) The Role of Cell Networks in Response to Diesel Exhaust Particles. AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE, 179.
  • Parker LC, Prestwich EC, Ward JR, Smythe E, Berry A, Triantafilou M, Triantafilou K & Sabroe I (2008) . J Immunol, 181(8), 5606-5617.
  • West PW, Parker LC, Ward JR & Sabroe I (2008) . Immunology, 125(1), 101-110.
  • Sabroe I, Parker LC, Calverley PMA, Dower SK & Whyte MKB (2008) . Postgrad Med J, 84(991), 259-264.
  • Sabroe I, Parker LC, Dower SK & Whyte MKB (2008) . J Pathol, 214(2), 126-135.
  • Sabroe I, Parker LC, Calverley PMA, Dower SK & Whyte MKB (2007) . Thorax, 62(8), 733-738.
  • Sabroe I, Parker LC, Dower SK & Whyte MKB (2007) . Proc Am Thorac Soc, 4(8), 606-610.
  • Parker LC, Prince LR & Sabroe I (2007) . Clin Exp Immunol, 147(2), 199-207.
  • Sabroe I, Parker LC, Dockrell DH, Davies DE, Dower SK & Whyte MKB (2007) . Am J Respir Crit Care Med, 175(4), 306-311.
  • Morris GE, Parker LC, Ward JR, Jones EC, Whyte MKB, Brightling CE, Bradding P, Dower SK & Sabroe I (2006) . FASEB J, 20(12), 2153-2155.
  • Parker LC, Jones EC, Prince LR, Dower SK, Whyte MKB & Sabroe I (2005) . J Leukoc Biol, 78(6), 1301-1305.
  • Parker LC, Whyte MKB, Dower SK & Sabroe I (2005) . J Leukoc Biol, 77(6), 886-892.
  • Parker LC, Whyte MKB, Vogel SN, Dower SK & Sabroe I (2004) . J Immunol, 172(8), 4977-4986.
  • Parker LC, Luheshi GN, Rothwell NJ & Pinteaux E (2002) . Br J Pharmacol, 136(2), 312-320.
  • Pinteaux E, Parker LC, Rothwell NJ & Luheshi GN (2002) . J Neurochem, 83(4), 754-763.
  • Sabroe I, Parker LC, Wilson AG, Whyte MKB & Dower SK (2002) . Clin Exp Allergy, 32(7), 984-989.
  • Sabroe IAN, Jones EC, Usher LR, Alapati S, Parker LC, Whyte MKB & Dower SK (2002) . Clinical Science, 103(s47), 55P-55P.
  • Touzani O, Boutin H, LeFeuvre R, Parker L, Miller A, Luheshi G & Rothwell N (2002) . J Neurosci, 22(1), 38-43.
  • Parker LC, Rushforth DA, Rothwell NJ & Luheshi GN (2000) . Brain Res Mol Brain Res, 79(1-2), 156-158.
  • Allan SM, Parker LC, Collins B, Davies R, Luheshi GN & Rothwell NJ (2000) . Proc Natl Acad Sci U S A, 97(10), 5580-5585.
  • Parker LC, Luheshi GN, Rothwell NJ & Pinteaux E (2000) Expression of the IL-1 type I receptor and accessory protein in mouse primary glial cell cultures. EUR J NEUROSCI, 12, 359-359.
  • Parker LC, Balderson DJ, Owen F, Rothwell NJ & Luheshi GN (1998) Interleukin-1 type-1 receptor expression in the rat hypothalamus. BRIT J PHARMACOL, 123, U106-U106.
  • Cody FW, Henley NC, Parker L & Turner G (1998) . Electroencephalogr Clin Neurophysiol, 109(1), 24-35.
  • Cody FWJ, Henley NC, Parker LC & Turner GR (1997) Autogenetic and reciprocal tonic reflex actions of muscle vibration-evoked afferent input studied in human wrist muscles.. J PHYSIOL-LONDON, 504P, P119-P119.

Book chapters

  • Prince L, Parker L & Sabroe I (2022) , Encyclopedia of Respiratory Medicine (pp. 264-270). Elsevier

Conference proceedings

  • Marsh EK, Prestwich EC, Marriott HM, Williams L, Hart AR, Muir CF, Parker LC, Jonker MR, Heijink IH, Timens W , Fife M et al (2018) . The influence of influenza: from cells to humans (pp A60.2-A60)
  • Mills J, Sabroe I, Midwood K & Parker L (2018) Human rhinovirus infection of airway epithelial cells induces tenascin-C release mas. INTERNATIONAL JOURNAL OF EXPERIMENTAL PATHOLOGY, Vol. 99(6) (pp A59-A59)
  • Bradley KL, Stokes CA, Parker LC & Condliffe AM (2017) . Cellular insights into lung injury repair (pp A112.1-A112)
  • Marsh EK, Prestwich EC, Marriott HM, Paiva C, Bennett JA, Jonker MR, Timens W, Heijink IH, Parker LC, Dockrell DH & Sabroe I (2016) The Role Of Pellino-1 In Modulating Signalling Pathways Controlling The Inflammatory Response To Viral Stimuli In Airway Epithelial Cells. AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE, Vol. 193
  • Ismail S, Roberts RL, Stokes CA, Juss JK, Sabroe I & Parker LC (2013) Phosphoinositide 3-kinase (PI3K) inhibition modulates responses to rhinovirus by mechanisms that are predominantly independent of autophagy. IMMUNOLOGY, Vol. 140 (pp 84-85)
  • Prestwich E, Paiva C, Parker L & Sabroe I (2013) The role of Pellino1 in modulating signalling pathways controlling the inflammatory response to viruses in airway epithelial cells. IMMUNOLOGY, Vol. 140 (pp 82-82)
  • Stokes CA, Glanville N, Kaur R, Hume RD, Robinson D, Perrie Y, Edwards MR, O'Donnell V, Harwood J, Parker LC & Sabroe I (2013) Phosphatidylserine-containing liposomes: modulators of rhinovirus induced inflammatory responses. IMMUNOLOGY, Vol. 140 (pp 108-108)
  • Parmar S, Thompson AAR, Higgins KR, Sabroe I, Parker LC, Lawrie A, Arnold J, Walker S, Elliot CA, Condliffe R , Kiely DG et al (2012) . D33. ASTHMA PATHOGENESIS (pp A5660-A5660)
  • Bennett JA, Prince LR, Stokes CA, Parker LC, Whyte MK & Sabroe I (2011) . THORAX, Vol. 66 (pp A60-A61)
  • Chaudhuri N, Jary H, Lea S, Khan N, Parker LC, Singh D & Sabroe I (2011) . THORAX, Vol. 66 (pp A114-A114)
  • Walmsley SR, Chilvers ER, Thompson A, Vaughan K, Marriott H, Parker L, Shaw G, Parmar S, Schneider M, Sabroe I , Dockrell D et al (2011) . C13. PATHOGENESIS OF ACUTE LUNG INJURY (pp A4009-A4009)
  • Jabeen M, Stokes CA, Prince LR, Sabroe I & Parker L (2011) The role of neutrophils as anti-inflammatory mediators of airway inflammation. CLINICAL AND EXPERIMENTAL ALLERGY, Vol. 41(12) (pp 1830-1830)
  • Jary H, Piddock K, Donaldson K, Prince LR, Parker LC, Sabroe I & Chaudhuri N (2010) . THORAX, Vol. 65 (pp A66-A67)
  • Stokes CA, Dick EP, Bennett JA, Ismail S, Edwards MR, Sabroe L & Parker LC (2010) . THORAX, Vol. 65 (pp A37-A38)
  • Chaudhuri N, Parker LC, Sabroe I & Donaldson K (2009) . THORAX, Vol. 64 (pp A54-A55)
  • Parker LC, Jones EC, Ward JR & Sabroe I (2007) Inhibition of TLR-induced inflammatory responses by SAPS. JOURNAL OF LEUKOCYTE BIOLOGY (pp 51-51)
  • West PW, Parker LC, Ward JR & Sabroe I (2007) Regulation of TLR induced human inflammatory responses by macrophage migration inhibitory factor. JOURNAL OF LEUKOCYTE BIOLOGY (pp 60-60)
  • Chaudhuri N, Donaldson K, Parker LC & Sabroe I (2007) The role of Cell networks in the response to Diesel Exhaust Particles (DEP).. JOURNAL OF LEUKOCYTE BIOLOGY (pp 25-25)
  • Parker LC, Jones EC, Morris GE, Dower SK, Whyte MK & Sabroe I (2006) The induction of antiviral responses in human airway smooth muscle and epithelial cells. THORAX, Vol. 61 (pp II9-II9)
  • Parker LC, Jones EC, Whyte MKB, Dower SK & Sabroe I (2005) Toll-like receptor (TLR) 4 activation induces tolerance in the human neutrophil. FASEB JOURNAL, Vol. 19(4) (pp A912-A912)
  • Parker LC, Jones EC, Whyte MK, Dower SK & Sabroe I (2004) Endotoxin tolerance in the human neutrophil. JOURNAL OF LEUKOCYTE BIOLOGY (pp 43-44)
  • Allan SM, Parker LC, Grundy RI & Collins B (2000) Site-specific actions of interleukin-1 in neurodegeneration. PHARMACOLOGY OF CEREBRAL ISCHEMIA 2000 (pp 425-431)
Teaching interests

I have created, developed, led and taught modules at both undergraduate and postgraduate level within the Faculties of Health and Science for many years, with a particular focus on immunology and the impact of viral infections on respiratory disease. 

I am also passionate about student support and welfare; I run an enhanced support programme for first year medical students as part of my role as Deputy Director of Phase 1, and support students in all phases of the MBChB in my role as a Associate Director of Student Affairs. I am also an academic tutor for undergraduate medical students, PGT and PGR students in the Medical school.

I am also committed to the continued improvement of teaching practice, supporting the development of others, and ultimately providing students with the very best learning experiences. My role as Faculty of Health representative for the Learning and Teaching Scholarship Network (LTSN) Steering committee allows me to support the ongoing development of colleagues across the University.

Teaching activities
  • Deputy Director of Phase 1 (MBChB)
  • Associate Director of Student Affairs (MBChB)
  • Deputy Programme Lead for BSc Medical Sciences Research Intercalation Programme 
  • MBChB Phase 2a Immunology Block Lead 
  • BSc in Biomedical Sciences Level 3 Module lead (Pharmacology of Respiratory Disease) 
  • Teaching on the MBChB, intercalated BSc and BSc Biomedical Sciences courses
  • Assessment MBChB – marking student selected components throughout the 5 year MBChB course; setting, quality assurance, standard setting and marking first and second year exams
  • Assessment BSc – setting and marking assignments for different modules on the Biomedical and intercalated BSc courses
  • Student support and academic tutoring
  • Curriculum design
  • Admissions – interviews for MBChB course
Professional activities and memberships
  • Fellow of the Higher Education Academy (FHEA).
  • Deputy Director of Phase 1 (MBChB)
  • Associate Director of Student Affairs (MBChB)
  • Deputy Programme Lead for BSc Medical Sciences Research Intercalation Programme 
  • Faculty of Health representative for the Learning and Teaching Scholarship Network (LTSN) Steering committee
  • SMPH Athena Swan Committee member 
  • SMPH Annual Research Meeting Working Group Committee member
  • SMPH HEA Fellowship Support / Mentor Scheme member
  • Member of the