What is the impact of EQ-5D-5L vs 3L on NICE Severity Weights?

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NICE currently recommends the EQ-5D instrument be scored using the 3-level (3L) value set. A new value set for the 5-level version (5L) will soon be publicly available. Policymakers in the UK health system, including NICE, need to know the likely impact of switching from 3L to 5L and one aspect of that is the impact on the severity modifier NICE applies in its technology appraisals programme.

The severity modifier is based on estimates of absolute and proportional shortfalls (AS and PS): the expected numbers of discounted QALYs for patients under current care compared to those for the general population. 

 

DSU Report

What is the impact of EQ-5D-5L vs 3L on NICE Severity Weights?

This report estimates the impact of switching from using the 3L to using the 5L by analysing 39 appraisal decisions in our main analysis and 18 appraisal decisions in a sensitivity sample. Reported impacts are the combined effects of differences in the descriptive systems and the value sets. These appraisals were conducted using NICE recommended 3L values for health states.