Professor John W Haycock
BSc (Hons) PhD
School of Chemical, Materials and Biological Engineering
Emeritus Professor
+44 114 222 5972
Full contact details
School of Chemical, Materials and Biological Engineering
Sir Robert Hadfield Building
Mappin Street
Sheffield
S1 3JD
- Profile
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John Haycock obtained his first degree and PhD in Biochemistry at Newcastle University and was a Research Fellow at Albany Medical College in New York, USA. He joined the department in 2001 as a Lecturer from the Medical School at Sheffield University. He was Engineering Faculty Director of Research and Innovation from 2016-19 and became Head of Materials Science and Engineering in 2019. His research and teaching covers fundamental and applied biomedical materials science through to engineering applications
- Qualifications
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BSc (Hons) Biochemistry, Newcastle University
PhD Neurology, Newcastle University
- Research interests
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John's research spans five interdisciplinary themes:
1. Nerve tissue engineering. The design of nerve guidance channels for repairing traumatic peripheral nerve injury 鈥 combining biomaterials, 3D fabrication, neuronal, glial and stem cell research.
2. 3D in vitro models of nerve. The use of 3D scaffolds and neuronal/glial co-cultures for 3D in vitro models of nerve as an alternative to animal models for disease, disorder and testing research.
3. 3D in vitro models of skin. The use of 3D scaffolds and keratinocyte/fibroblast co-cultures for 3D in vitro models of skin as an alternative to animal models for inflammatory testing.
4. 3D Imaging and technology development for bioscience applications Established confocal microscopy, 2-photon microscopy, time-resolved microscopy, light sheet microscopy and in vivo confocal microscopy facilities for a wide range of biomaterials and regenerative medicine research at Sheffield University
5. Bioactive surfaces. Creation of biologically active surfaces for medical device applications
Key projects
- EPSRC Centre for Doctoral Training in Advanced Biomedical Materials with Manchester University (Professor Sarah Cartmell (PI) and Professor Julie Gough)
- 3D BioNet: An integrated technological platform for 3D micro-tissues. Technology Touching Life - BBSRC, MRC, EPSRC with Dr Raphael L茅vy (PI), Professor Helen Byrne, Professor Paola Borri, Professor Stefan Przyborski, Dr Marianne Ellis, Dr Chris Goldring and Professor Ruth Cameron
- Sir Henry Royce Institute - Sheffield Equipment - EPSRC, with Professor Mark Rainforth (PI), Professor Dan Allwood, Professor Ian Reaney, Professor Iain Todd, Professor Neil Hyatt and Professor Derek Sinclair
- Sir Henry Royce Institute - Sheffield Build - EPSRC, with Professor Mark Rainforth (PI), Professor Dan Allwood, Professor Ian Reaney, Professor Iain Todd, Professor Neil Hyatt and Professor Derek Sinclair
- Development and validation of a human brain micro physiological system derived from induced pluripotent stem cells in amyotrophic lateral sclerosis (ALS) 3D BioNet, with Dr Ke Ning (PI)
- The Design, Manufacture and Testing of Advanced Nerve Guidance Conduits. Dr Jeff Wadsworth - Battelle Memorial Institute. With SUNY, New York 鈥 Melendez A, as PI with Dr Fred Claeyssens and Professor Fiona Boissonade
Previous major projects
- Cellular Force Microscope - BBSRC with Professor Jamie Hobbs and Dr N Brown.
- Affordable Healthcare in Pakistan - Developing Biomedical Materials for Clinical Impact. EPSRC (GCRF)
- NEURIMP (FP7) - Novel combination of biopolymers and manufacturing technologies for production of a peripheral nerve implant containing an internal aligned channels array. An EC funded project with 8 EU partners.
- IPROMEDAI - Improved Protection of Medical Devices Against Infection. An EU COST (European Cooperation in Science & Technology) network across 24 countries. UK Management Committee member.
- Dinuclear ruthenium light-switches as multi-output sub-cellular imaging probes within live cells and tissues. EPSRC (with Dr James Thomas, Dr Julia Weinstein and Prof Sheila MacNeil).
- EPSRC Centre for Doctoral Training in Polymers, Soft Matter and Colloids (with Professor Steve Armes, Professor David Lidzey, Professor Neil Hopkinson, Professor Graham Leggett.
- Novel 3D coating of bioactive glass and metallic composites. EPSRC/Innovate UK (with Prof Mark Rainforth and Prof Iain Todd).
- Development of a 3D engineered skin model for inflammatory detection (EPSRC).
- The development of xenogenic decellularised nerve graft for traumatic repair (EPSRC).
- Toward the next generation of joint repair strategies. Using plasma polymerization to produce bioinspired, biofunctional, biomaterial implants (Dunhill Medical Trust) 鈥 with Dr Aileen Crawford and Dr Dave Buttle.
- Development of early melanoma detection using O2 probes and time-resolved emission imaging microscopy (BBSRC) 鈥 with Dr Julia Weinstein.
- Sensor Integrated Bioreactors (TSB) 鈥 with Dr Jon Aylott, Kirkstall Ltd and Locate Therapeutics (formerly Regentec Ltd).
- Cross-cutting Directors of Research and Innovation - Interdisciplinary PhD Scholarships. The Construction of Human Perfection (with Prof Tammy Hervey, Prof Paul Hatton, Prof Adam Piette, Dr Fabienne Collignon, Dr Sarah Baker, Dr Keith Smith, Dr Amanda Warren-Jones).
Research themes/centres
John鈥檚 research and opinion on nerve injury repair has been featured in a number of recent media publications:
- BBC World News 鈥淪cience in Action鈥 -
- BBC World News 鈥淗orizons鈥 鈥 (with colleague Dr Fred Claeyssens)
- YouTube 鈥 Research@Sheffield - Tissue Engineering 鈥
- The Daily Telegraph -
- The Daily Mail -
- Publications
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Books
- Preface.
Edited books
- . Singapore: Pan Stanford Publishing.
Journal articles
- . Journal of Biotechnology.
- . International Journal of Biological Macromolecules, 278, 134774-134774.
- . Regenerative Biomaterials, 10.
- . Macromolecular Bioscience, 23(11).
- . ACS Biomaterials Science & Engineering, 9(3), 1472-1485.
- . RSC Medicinal Chemistry, 14(1), 65-73.
- . Trends in Molecular Medicine, 28(4), 331-342.
- . Journal of Colloid and Interface Science, 603, 380-390.
- . Journal of the American Chemical Society, 143(48), 20442-20453.
- . Frontiers in Materials, 8.
- . ACS Applied Materials & Interfaces, 13(28), 32624-32639.
- . Journal of Biomedical Materials Research Part B: Applied Biomaterials, 109(11), 1713-1723.
- . Molecules, 26(5).
- . ACS Biomaterials Science & Engineering, 7(2), 672-689.
- . Progress in Natural Science: Materials International, 30(5), 686-696.
- . Biomedical Materials, 15(4).
- . Biotechnology and Bioengineering, 117(10), 3124-3135.
- . Polymers, 12(4).
- . Journal of the American Chemical Society, 142(10), 4639-4647.
- . CHEMICAL SCIENCE, 11(9), 2566-2566.
- . Journal of Tissue Engineering and Regenerative Medicine, 13(9), 1581-1594.
- . The FASEB Journal, 33(S1).
- . Chemical Science, 10(12), 3502-3513.
- . International Journal of Bioprinting, 4(1).
- . Acta Biomaterialia, 78, 48-63.
- . In Vivo, 32(3), 461-472.
- . International Materials Reviews, 64(2), 91-126.
- . Scientific Reports, 7.
- . Biotechnology and Bioengineering, 113(9), 2041-2053.
- . Biofabrication, 8(1).
- . Materials Science and Engineering: C, 58, 1199-1206.
- . Respiratory Research, 16.
- Protest music as adult education and learning for social change: a theorisation of a public pedagogy of protest music. AUSTRALIAN JOURNAL OF ADULT LEARNING, 55(3), 423-442.
- . Journal of Anatomy, 227(3), 302-314.
- . Engineering in Life Sciences, 15(6), 612-621.
- . Journal of Biomedical Optics , 20(7).
- . Biomaterials, 49, 77-89.
- . Soft Matter, 11(38), 7567-7578.
- . RSC Advances, 4(66), 35003-35008.
- Development of 3D skin models for in vitro testing. JOURNAL OF TISSUE ENGINEERING AND REGENERATIVE MEDICINE, 8, 377-377.
- Development of an acellular xenogeneic nerve graft. JOURNAL OF TISSUE ENGINEERING AND REGENERATIVE MEDICINE, 8, 405-405.
- . Molecular Pharmaceutics, 11(7), 2082-2091.
- . Angewandte Chemie, 126(13), 3435-3439.
- . Journal of Biophotonics, 7(10), 761-765.
- . Chemical Science, 5(3), 879-886.
- . SPIE Proceedings, 8923, 89231A-89231A.
- . Journal of Cosmetics, Dermatological Sciences and Applications, 03(03), 175-189.
- . Scientific Reports, 3.
- . Biotechnology and Bioengineering, 110(8), 2277-2291.
- . SPIE Proceedings, 8579, 85790C-85790C.
- . Nature Protocols, 7(11), 1996-2004.
- . Biomaterials, 33(25), 5901-5913.
- Development of a 3D neuronal glial co-culture model for peripheral nerve studies and repair strategies. JOURNAL OF TISSUE ENGINEERING AND REGENERATIVE MEDICINE, 6, 352-352.
- RGD functionalised highly branched poly(N-isopropylacrylamide) (HB-p(NIPAM)) semi interpenetrating polymer networks (semi-IPNs) for peripheral nerve repair. JOURNAL OF TISSUE ENGINEERING AND REGENERATIVE MEDICINE, 6, 78-79.
- Investigating maleic anhydride and acrylic acid plasma polymers as coatings for peripheral nerve guide conduits. JOURNAL OF TISSUE ENGINEERING AND REGENERATIVE MEDICINE, 6, 76-76.
- Functionalised degrable photocurable polymers for peripheral nerve repair. JOURNAL OF TISSUE ENGINEERING AND REGENERATIVE MEDICINE, 6, 78-78.
- An aligned 3D neuronal-glial co-culture model for peripheral nerve studies. Biomaterials.
- . Biofabrication, 4(2), 025005-025005.
- . International Gambling Studies, 12(1), 111-127.
- . Experimental Dermatology, 21(2), 158-160.
- . Tissue Engineering Part B: Reviews, 18(2), 116-128.
- , 344-364.
- Directing neuronal cell outgrowth and schwann cell organisation with aligned polycaprolactone microfibre scaffolds. 24th European Conference on Biomaterials Annual Conference of the European Society for Biomaterials.
- Adipose-derived stem cells (ASCs) for peripheral nerve repair. 24th European Conference on Biomaterials Annual Conference of the European Society for Biomaterials.
- . 2011 Conference on Lasers and Electro Optics Europe and 12th European Quantum Electronics Conference CLEO Europe Eqec 2011.
- . Glia, 59(5), 734-749.
- Improving nerve guidance conduits with biodegradable aligned microfibres. European Cells and Materials, 22(SUPPL.2), 1.
- The use of plasma polymerised acrylic acid and maleic anhydride for neuronal cell engineering. European Cells and Materials, 22(SUPPL.3), 23.
- Directing neuronal cell outgrowth and schwann cell organisation with aligned polycaprolactone microfibre scaffolds. European Cells and Materials, 22(SUPPL.3), 17.
- Adipose-derived stem cells (ASCs) for peripheral nerve repair. European Cells and Materials, 22(SUPPL.2), 9.
- Microstructuring of photocurable biomaterials with applications in neuronal repair. European Cells and Materials, 22(SUPPL.3), 15.
- Adipose-derived stem cells for peripheral nerve repair. European Cells and Materials, 22(SUPPL.3), 16.
- Development of a tissue-engineered skin model for detecting irritants. European Cells and Materials, 22(SUPPL.2), 23.
- . Biofabrication, 3(4), 045005-045005.
- , Methods in Molecular Biology, Vol. 695, 155-166.
- , Methods in Molecular Biology, Vol. 695, 1-15.
- , 19-28.
- A Novel 3D Immuno-Competent Co-Cultured Skin Model to Investigate the Allergenic Potential of Chemicals. JOURNAL OF PHARMACY AND PHARMACOLOGY, 62(10), 1241-1242.
- . Biotechnology and Bioengineering, 106(5), 794-803.
- . Applied Physics Letters, 96(23).
- . Applied Physics Letters, 96(19), Art no.192503.
- . IEEE Magnetics Letters, 1, 1500104-1500104.
- . Proceedings of the Institution of Mechanical Engineers, Part H: Journal of Engineering in Medicine, 224(12), 1509-1521.
- . Soft Matter, 5(24), 4928-4928.
- . Advanced Materials, 21(28), 2909-2915.
- The use of aligned polymer microfibres in peripheral nerve engineering. European Cells and Materials, 18(SUPPL. 2), 82.
- Adipose-derived stem cells (ASCs) for peripheral nerve repair. European Cells and Materials, 18(SUPPL. 2), 23.
- . Journal of Endodontics, 35(9), 1264-1269.
- . SPIE Newsroom.
- . Physiological Research, 669-684.
- In vivo analysis on the early response of electrospun poly-DL-lactide (PDLA) and polyglycolic acid (PGA) 3D scaffolds for tissue engineering. 8th World Biomaterials Congress 2008, 1, 253.
- Mesenchymal stems cells and endothelial cells on micropatterned surfaces prepared by plasma polymerisation. 8th World Biomaterials Congress 2008, 3, 1480.
- Use of aligned polymer microfibres for peripheral nerve repair. 8th World Biomaterials Congress 2008, 1, 260.
- Long term degradation study of electrospun scaffolds for soft tissue reconstruction. 8th World Biomaterials Congress 2008, 1, 2.
- . Proceedings of the National Academy of Sciences, 105(42), 16071-16076.
- Peripheral nerve engineering using aligned polymer microfibres. European Cells and Materials, 16(SUPPL. 3), 15.
- . Biomaterials, 29(21), 3091-3104.
- . Peptides, 29(6), 1004-1009.
- Development of a synthetic matrix to replace human dermis. European Cells and Materials, 16(SUPPL. 3), 4.
- . Biotechnology and Bioengineering, 99(5), 1250-1260.
- Evaluation of anti-inflammatory and antimicrobial resorcinarene-peptides for biomaterial modification. European Cells and Materials, 14(SUPPL.3), 23.
- Evaluation of anti-inflammatory and antimicrobial resorcinarene-peptides for biomaterial modification. European Cells and Materials, 14(SUPPL.3), 126.
- . Journal of Neurochemistry, 103(4), 1567-1573.
- . Tissue Engineering, 13(5), 1013-1024.
- . American Journal of Physiology-Endocrinology and Metabolism, 293(1), E48-E56.
- . Tetrahedron Letters, 48(8), 1317-1319.
- . Journal of Materials Science: Materials in Medicine, 18(2), 321-328.
- . Biotechnology and Bioengineering, 97(5), 1318-1328.
- . American Journal of Physiology-Endocrinology and Metabolism, 292(3), E788-E801.
- . Vascular Pharmacology, 45(3), e85-e85.
- . Journal of Leukocyte Biology, 80(4), 897-904.
- . Melanoma Research, 16(1), 11-22.
- . Laboratory Investigation, 86(8), 781-789.
- Evaluation of anti-inflammatory calixarene-peptides for biomaterial modification. European Cells and Materials, 11(SUPPL.2), 26.
- Anti-inflammatory peptide approaches for preventing vascular inflammation. European Cells and Materials, 11(SUPPL.2), 45.
- . Biomaterials, 27(18), 3459-3465.
- . Journal of Biotechnology, 122(3), 372-381.
- . Peptides, 27(2), 421-430.
- . Peptides, 27(2), 431-437.
- . Peptides, 27(2), 444-452.
- . Tissue Engineering, 11(11-12), 1824-1831.
- . Science, 309(5733), 401-404.
- Anti-inflammatory peptide Approaches for Preventing vascular inflammation. European Cells and Materials, 10(SUPPL.2), 17.
- . Peptides, 26(7), 1150-1158.
- . Tissue Engineering, 11(7-8), 1023-1033.
- . Journal of Comparative Neurology, 481(4), 352-362.
- Smart scaffolds or smart cells? Steps towards the development of a synthetic scaffold for skin reconstruction. Transactions 7th World Biomaterials Congress, 567.
- Anti-inflammatory and cytoprotective action of novel synthetic MSH peptides in human skin keratinocytes. Transactions 7th World Biomaterials Congress, 1067.
- 伪-melanocyte stimulating hormone anti-inflammatory action in human dermal fibroblast cells: Application in skin tissue engineering. Transactions 7th World Biomaterials Congress, 1069.
- . Wound Repair and Regeneration, 12(6), 626-634.
- . Journal of Neurochemistry, 91(2), 374-384.
- . European Journal of Neuroscience, 20(4), 1108-1112.
- . Journal of Materials Science: Materials in Medicine, 15(7), 743-749.
- . Journal of Neurochemistry, 90(1), 245-254.
- . The Journal of Neuroscience, 24(17), 4242-4249.
- . British Journal of Cancer, 90(7), 1457-1463.
- . NeuroReport, 15(3), 493-498.
- . Journal of Investigative Dermatology, 122(4), 1010-1019.
- . Journal of Biological Chemistry, 279(3), 2182-2191.
- . British Journal of Cancer, 89(10), 2004-2015.
- . Hypertension, 42(6), 1130-1136.
- . Pigment Cell Research, 16(5), 598-598.
- . Pigment Cell Research, 16(5), 597-598.
- . Journal of Neurochemistry, 87(3), 574-585.
- Measurement of NF-魏B as an indicator of stress in skin cells in 2D culture and a 3D reconstructed skin model. European Cells and Materials, 6(SUPPL. 2), 51.
- Alpha-MSH inhibits inflammatory signalling in glial cells. European Cells and Materials, 6(SUPPL. 2), 52.
- 伪-melanocyte stimulating hormone anti-inflammatory action in human dermal fibroblast cells. European Cells and Materials, 6(SUPPL. 2), 42.
- . Journal of Investigative Dermatology, 121(3), 557-563.
- . Proceedings of the National Academy of Sciences, 100(7), 4305-4309.
- . Neuroreport, 14(17), 2171-2175.
- -msh inhibits inflammatory signalling in olfactory ensheathing cells. Neuroreport, 14(17), 749-755.
- . European Journal of Biochemistry, 269(24), 6133-6141.
- 伪-melanocyte-stimulating hormone anti-inflammatory action in human dermal fibroblast cells. European Cells and Materials, 4(SUPPL. 2), 50.
- Proopiomelanocortin anti-inflammatory peptide signalling in human skin keratinocyte cells. European Cells and Materials, 4(SUPPL. 2), 46.
- . European Journal of Pharmacology, 449(1-2), 71-74.
- . Journal of Neurochemistry, 82(2), 382-388.
- Melanoma cell attachment, invasion and integrin expression is upregulated by the proinflammatory cytokine TNF-伪 and suppressed by the anti-inflammatory peptide 伪-MSH. BRITISH JOURNAL OF CANCER, 86, S94-S94.
- . Journal of Neurochemistry, 81(5), 947-953.
- . Journal of Neuroscience Methods, 116(1), 29-34.
- . Journal of Neurochemistry, 81(3), 589-593.
- . Annals of Neurology, 51(5), 637-641.
- . Journal of Neuroscience Methods, 114(2), 205-212.
- . European Journal of Neuroscience, 15(4), 769-773.
- Alpha-melanocyte stimulating hormone inhibits porcine vascular smooth muscle and endothelial cell responses to tumor necrosis factor-alpha. JOURNAL OF THE AMERICAN COLLEGE OF CARDIOLOGY, 39(5), 54A-54A.
- . Journal of Investigative Dermatology, 119(6), 1244-1253.
- . Journal of Investigative Dermatology, 119(5), 1165-1171.
- . Journal of Neurochemistry, 79(2), 349-360.
- . Pigment Cell Research, 14(4), 298-309.
- . European Journal of Neuroscience, 13(4), 773-780.
- 伪-MSH peptides inhibit cytokine-stimulated NF-魏B/p65 activation in HaCaT keratinocytes. JOURNAL OF INVESTIGATIVE DERMATOLOGY, 117(2), 425-425.
- . Neuropsychopharmacology, 24(5), 561-567.
- Cellular and hormonal regulation of pigmentation in human choroidal and iridial melanocytes.. INVESTIGATIVE OPHTHALMOLOGY & VISUAL SCIENCE, 42(4), S214-S214.
- Cloning and confocal microscopy of mGluR6 in the rabbit retina. INVESTIGATIVE OPHTHALMOLOGY & VISUAL SCIENCE, 42(4), S375-S375.
- . Journal of Neurochemistry, 74(6), 2470-2477.
- . Journal of Neurochemistry, 75(1), 225-232.
- . European Journal of Neuroscience, 12(11), 3823-3832.
- . The Journal of Neuroscience, 20(19), 7297-7306.
- . Journal of Neuroscience Methods, 99(1-2), 37-44.
- . Journal of Chemical Neuroanatomy, 19(2), 105-116.
- . Journal of Biological Chemistry, 275(21), 15629-15636.
- Investigation of uveal melanocyte pigmentation. INVESTIGATIVE OPHTHALMOLOGY & VISUAL SCIENCE, 41(4), S771-S771.
- . European Journal of Neuroscience, 11(10), 3499-3511.
- . Annals of the New York Academy of Sciences, 885(1), 396-399.
- . Biological Psychiatry, 46(9), 1275-1286.
- . Neurology, 53(5), 1032-1032.
- . Molecular Pharmacology, 55(2), 202-209.
- . Journal of Investigative Dermatology, 113(4), 560-566.
- . Current Eye Research, 17(8), 813-822.
- . Journal of Neurochemistry, 71(4), 1670-1675.
- . Journal of Neurochemistry, 70(5), 1809-1818.
- . NeuroReport, 9(10), 2201-2207.
- . The Journal of Neuroscience, 18(11), 4119-4132.
- Lack of phosphorylation or activation of aromatic L-amino acid decarboxylase in chromaffin cells by treatments which increase catecholamine biosynthesis.. FASEB JOURNAL, 12(8), A1468-A1468.
- Regulation of the phosphorylation state of tyrosine hydroxylase in vivo at multiple sites: Effects of haloperidol and raclopride in dorsal and ventral striatum. FASEB Journal, 12(4).
- . British Journal of Dermatology, 138(1), 45-56.
- Evidence for an immunomodulatory role for 伪-MSH in cutaneous and ocular melanoma. British Journal of Cancer, 78(2), 156-157.
- . Current Eye Research, 17(8), 813-822.
- . Burns, 23(7-8), 533-540.
- . Neuroscience, 82(3), 727-738.
- Presynaptic dopaminergic markers in human striatum during development and aging.. FASEB JOURNAL, 11(9), A1259-A1259.
- Role of intracellular calcium in co-regulation of RPE cell contraction and proliferation by platelet mitogens.. INVESTIGATIVE OPHTHALMOLOGY & VISUAL SCIENCE, 38(4), 3490-3490.
- . Schizophrenia Research, 24(1-2), 63-64.
- . Experimental Neurology, 144(1), 69-73.
- . Journal of Neurochemistry, 67(2), 629-635.
- . NeuroReport, 8(1), 357-361.
- Peptide substrates for assaying the in situ regulation of erk1/erk2 activity. FASEB Journal, 10(6), A1266.
- . Acta Neuropathologica, 92(4), 331-340.
- . Brain Research, 727(1-2), 1-12.
- . Nature Medicine, 2(6), 699-703.
- . Clinica Chimica Acta, 249(1-2), 47-58.
- . Biochemistry, 35(18), 5641-5646.
- Allergen-induced upregulation of intracellular adhesion molecule-1 in keratinocytes. JOURNAL OF INVESTIGATIVE DERMATOLOGY, 106(4), 702-702.
- . Contemporary Sociology, 25(2), 250-250.
- . British Journal of Pharmacology, 116(4), 2310-2314.
- . Movement Disorders, 10(1), 10-17.
- . Annals of Neurology, 38(2), 260-264.
- . Journal of Neurochemistry, 64(5), 2281-2287.
- . Schizophrenia Research, 15(1-2), 59-59.
- . The Journal of Neuroscience, 15(2), 1285-1297.
- . Neuropsychopharmacology, 11(4), 272-272.
- . Journal of Neurochemistry, 62(2), 680-685.
- . Brain Research, 656(1), 1-13.
- . Annals of the Rheumatic Diseases, 53(6), 396-399.
- REPORT ON THE 14TH ALTERNATIVE-MUSCLE-CLUB CONFERENCE, 19-21 DECEMBER 1993, UNIVERSITY OF NEWCASTLE-UPON-TYNE, UK. JOURNAL OF MUSCLE RESEARCH AND CELL MOTILITY, 15(2), 172-173.
- . Journal of Neurochemistry, 60(2), 493-502.
- . Proceedings of the National Academy of Sciences, 90(16), 7603-7607.
- . Analytical Biochemistry, 208(2), 397-399.
- . Neuroscience, 54(2), 477-492.
- . Neurochemical Research, 18(1), 15-26.
- . Journal of Neurochemistry, 58(2), 494-502.
- . Journal of Neurochemistry, 58(1), 57-64.
- . Journal of Neurochemistry, 59(1), 147-156.
- . Journal of Biological Chemistry, 267(18), 12639-12646.
- . Proceedings of the National Academy of Sciences, 89(6), 2365-2369.
- . Regulatory Peptides, 37(3), 332-332.
- Reproduction of autoradiograms and gels with contact negatives and prints. Biotechniques, 12(3), 378-379.
- . Brain Research Bulletin, 29(6), 931-942.
- Preparative peptide purification by cation-exchange and reversed-phase perfusion chromatography. Biotechniques, 12(5), 742-747.
- . Journal of Neurochemistry, 56(6), 2139-2142.
- . Journal of Biological Chemistry, 266(15), 9347-9350.
- . Journal of Biological Chemistry, 266(9), 5650-5657.
- . The Journal of Neuroscience, 10(8), 2649-2659.
- PHOSPHORYLATION OF TYROSINE-HYDROXYLASE INSITU AT SERINE-8, SERINE-19, SERINE-31, AND SERINE-40. JOURNAL OF BIOLOGICAL CHEMISTRY, 265(20), 11682-11691.
- . Journal of Biological Chemistry, 265(20), 11682-11691.
- . Experimental Brain Research, 81(1).
- FLUORESCENT WHITE-LIGHT CONVERTS TRANS-UROCANIC TO CIS-UROCANIC ACID INVITRO. CLINICAL RESEARCH, 38(1), A13-A13.
- Co-localization of choline acetyltransferase and tyrosine hydroxylase within neurons of the dorsal motor nucleus of the vagus. Journal of Chemical Neuroanatomy, 3(2), 133-140.
- . Journal of Neurochemistry, 52(1), 274-284.
- . Journal of Neurochemistry, 52(2), 521-529.
- . Journal of Comparative Neurology, 279(3), 397-414.
- . Analytical Biochemistry, 181(2), 259-266.
- . Experimental Brain Research, 73(2).
- . The Journal of Neuroscience, 8(9), 3233-3239.
- . Proceedings of the National Academy of Sciences, 85(5), 1677-1681.
- . Neurotoxicology and Teratology, 10(5), 461-464.
- . Brain Research Bulletin, 21(2), 305-312.
- . Journal of Neurochemistry, 48(2), 615-621.
- . Journal of Comparative Neurology, 266(3), 307-318.
- . Brain Research Bulletin, 19(6), 619-622.
- . Neurochemistry International, 7(2), 301-308.
- . Proceedings of the National Academy of Sciences, 81(24), 7713-7717.
- THE BASAL GANGLIA AND AGING. AGE, 7(4), 145-145.
- TECHNIQUE FOR THE LOCALIZATION OF TYROSINE HYDROXYLASE-LIKE IMMUNOREACTIVITY. ANATOMICAL RECORD, 208(3), A144-A144.
- THE LOCALIZATION OF TYROSINE HYDROXYLASE-LIKE IMMUNOREACTIVITY IN THE NUCLEUS ACCUMBENS OF THE MOUSE. ANATOMICAL RECORD, 208(3), A31-A31.
- . Peptides, 5, 263-268.
- . Brain Research Bulletin, 13(1), 109-126.
- . Mechanisms of Ageing and Development, 24(3), 293-307.
- . Journal of Neuroscience Methods, 7(4), 329-351.
- . Journal of Biological Chemistry, 257(16), 9416-9423.
- . Journal of Biological Chemistry, 257(22), 13699-13703.
- . Journal of Biological Chemistry, 257(21), 12641-12648.
- . Journal of Biological Chemistry, 257(21), 12632-12640.
- PHOSPHORYLATION AND ACTIVATION OF TYROSINE-HYDROXYLASE MEDIATE THE ACETYLCHOLINE-INDUCED INCREASE IN CATECHOLAMINE BIOSYNTHESIS IN ADRENAL CHROMAFFIN CELLS. JOURNAL OF BIOLOGICAL CHEMISTRY, 257(21), 2641-2648.
- PHOSPHORYLATION AND ACTIVATION OF TYROSINE-HYDROXYLASE MEDIATE THE CAMP-INDUCED INCREASE IN CATECHOLAMINE BIOSYNTHESIS IN ADRENAL CHROMAFFIN CELLS. JOURNAL OF BIOLOGICAL CHEMISTRY, 257(21), 2632-2640.
- MULTIPLE SITE PHOSPHORYLATION OF TYROSINE-HYDROXYLASE - DIFFERENTIAL REGULATION INSITU BY 8-BROMO-CAMP AND ACETYLCHOLINE. JOURNAL OF BIOLOGICAL CHEMISTRY, 257(22), 13699-13703.
- . Molecular Pharmacology, 15(1), 78-85.
- . Neuroscience, 4(9), 1341-1346.
- . Journal of Neurochemistry, 30(5), 1113-1125.
- . Nature, 276(5684), 194-195.
- . Brain Research, 155(1), 192-195.
- . European Journal of Pharmacology, 51(3), 261-273.
- . Brain Research, 150(3), 642-647.
- . Naunyn-Schmiedeberg's Archives of Pharmacology, 301(3), 175-179.
- . Life Sciences, 21(12), 1837-1843.
- . Biochemical Pharmacology, 26(2), 159-161.
- . BEHAVIORAL BIOLOGY, 21(4), 508-528.
- . Experimental Neurology, 57(3), 873-882.
- . Behavioral Biology, 20(2), 197-204.
- . Experimental Neurology, 54(2), 199-208.
- . Psychopharmacology, 54(1), 21-24.
- . Psychopharmacology, 53(2), 213-215.
- . Behavioral Biology, 20(3), 281-310.
- . Behavioral Biology, 21(4), 508-528.
- . British Journal of Pharmacology, 58(4), 569-572.
- . Brain Research, 115(2), 243-256.
- . Journal of Theoretical Biology, 60(1), 109-130.
- . The Journal of Physiology, 254(2), 475-505.
- . Pharmacology Biochemistry and Behavior, 5(5), 525-528.
- K+ dependent release of gaba from isolated brain synaptosomes: secretion?. Trans Amer Soc Neurochem, 7(1), No.312.
- . BEHAVIORAL BIOLOGY, 14(3), 387-402.
- . Behavioral Biology, 14(3), 387-402.
- . Science, 186(4169), 1135-1136.
- . Science, 186(4169), 1136-1136.
- . Molecular Pharmacology, 10(3), 438-449.
- RETROGRADE-AMNESIA AND REMINDER EFFECT - REPLY. SCIENCE, 186(4169), 1136-1136.
- . Science, 180(4091), 1199-1201.
- . Experimental Neurology, 41(1), 201-213.
- . Physiology & Behavior, 11(1), 99-102.
- . Behavioral Biology, 9(1), 123-127.
- . International Journal of Bioprinting, 2(1), 35-35.
- . Biotechnology and Bioengineering.
- . Biomedical Materials, 9(4), 045009-045009.
- . Biofabrication, 5(3), 035011-035011.
- . Carcinogenesis, 28(11), 2268-2273.
- . Soft Matter, 3(8), 971-973.
- . Annals of the New York Academy of Sciences, 805(1), 219-230.
Book chapters
- , Reference Series in Biomedical Engineering (pp. 245-279). Springer International Publishing
- , The Handbook of Polyhydroxyalkanoates (pp. 255-284). CRC Press
- , Peripheral Nerve Tissue Engineering and Regeneration (pp. 1-35). Springer International Publishing
- , Cell Engineering and Regeneration (pp. 215-236). Springer International Publishing
- , Cell Engineering and Regeneration (pp. 1-22). Springer Nature
- , Optical Techniques in Regenerative Medicine (pp. 46-77). CRC Press
- Fluorescence Microscopy, Optical Techniques in Regenerative Medicine (pp. 29-59).
- In Haycock J, Ahluwalia A & Wilkinson J (Ed.), Cellular in Vitro Testing: Methods and Protocols (pp. 109-121). Singapore: Pan Stanford.
- , Scaffolds for Tissue Engineering (pp. 20-39). Jenny Stanford Publishing
- , Scaffolds for Tissue Engineering Biological Design Materials and Fabrication (pp. 57-78).
- Development of a Paracrine-Signaling Model for Detecting Irritancy Using Human Keratinocytes and Fibroblasts, CELLULAR IN VITRO TESTING: METHODS AND PROTOCOLS (pp. 109-121).
- CELLULAR IN VITRO TESTING METHODS AND PROTOCOLS Preface, CELLULAR IN VITRO TESTING: METHODS AND PROTOCOLS (pp. XIII-XV).
- , Surface Modification of Biomaterials (pp. 344-364). Elsevier
- , Surface Modification of Biomaterials (pp. xi-xiv). Elsevier
- , Oxidative Stress in Skeletal Muscle (pp. 157-176). Birkh盲user Basel
- , Function and Regulation of Monoamine Enzymes: Basic and Clinical Aspects (pp. 121-129). Palgrave Macmillan UK
- , Catecholamines: Basic and Clinical Frontiers (pp. 40-42). Elsevier
- , Progress in Brain Research (pp. 151-162). Elsevier
Conference proceedings
- Developing 3D Peripheral Nerve Injury models for Long term analysis of Materials. TISSUE ENGINEERING PART A, Vol. 29(13-14)
- Developing 3D Peripheral Nerve Injury models for Long term analysis of Materials. TISSUE ENGINEERING PART A, Vol. 29(13-14)
- BIOACTIVE 3D SCAFFOLDS FOR THE DELIVERY OF NEUROTROPHINS TO IMPROVE NEURITE OUTGROWTH AND INDUCE SCHWANN CELL MIGRATION. TISSUE ENGINEERING PART A, Vol. 28 (pp S602-S602)
- BIOMATERIAL SURFACE FUNCTIONALIZATION FOR SUSTAINED DELIVERY OF NGF AND BDNF TO STIMULATE NEURITE GROWTH. TISSUE ENGINEERING PART A, Vol. 28 (pp S51-S51)
- A NEXT GENERATION BIO-INSPIRED DEVICE FOR EFFECTIVE PERIPHERAL NERVE REGENERATION. TISSUE ENGINEERING PART A, Vol. 28 (pp S293-S294)
- THE INCORPORATION OF A NATIVE-LIKE EXTRACELLULAR MATRIX IN NERVE GUIDE CONDUITS FOR PERIPHERAL NERVE REPAIR. TISSUE ENGINEERING PART A, Vol. 28 (pp S376-S376)
- AMINE MODIFIED POLYCAPROLACTONE SCAFFOLDS FOR PERIPHERAL NERVE REPAIR. TISSUE ENGINEERING PART A, Vol. 28 (pp S337-S337)
- In situ repair of full-thickness cartilage defects using biomimetic biofunctionalised implants. INTERNATIONAL JOURNAL OF EXPERIMENTAL PATHOLOGY, Vol. 99(6) (pp A17-A17)
- . Basic Science (pp A78.1-A78)
- . International Journal of Experimental Pathology, Vol. 98(3) (pp A15). Oxford, UK, 3 May 2017 - 3 May 2017.
- 3D Printing and Plasma Coating of Nerve Guide Conduits (NGC). TISSUE ENGINEERING PART A, Vol. 21 (pp S359-S360)
- Nerve Tissue Engineering using Blends of Polyhydroxyalkanoates for Peripheral Nerve Regeneration. TISSUE ENGINEERING PART A, Vol. 21 (pp S325-S325)
- PERIPHERAL NERVE REGENERATION USING BLENDS OF POLYHYDROXYALKANOATES. JOURNAL OF THE PERIPHERAL NERVOUS SYSTEM, Vol. 20(2) (pp 185-185)
- . The FASEB Journal, Vol. 29(S1)
- . ALTEX (pp 441-477)
- Nerve guides from photocurable polymers for peripheral nerve repair. JOURNAL OF TISSUE ENGINEERING AND REGENERATIVE MEDICINE, Vol. 8 (pp 172-172)
- Oxygen difference in live melanoma muticellular tumour spheroids using novel platinum compound and time-resolved imaging microscopy. JOURNAL OF TISSUE ENGINEERING AND REGENERATIVE MEDICINE, Vol. 8 (pp 314-314)
- Time-resolved two-photon emission imaging microscopy with transition metal complexes (TPE-TREM). ABSTRACTS OF PAPERS OF THE AMERICAN CHEMICAL SOCIETY, Vol. 245
- Human hair follicle dermal cells and skin fibroblasts show differential activation of NF-魏B in response to pro-inflammatory challenge. Experimental Dermatology
- Hyaluronan as a potential mechanotransduction mediator. European Cells and Materials, Vol. 22(SUPPL.2) (pp 6)
- The Response of Matrix Synthesizing MLO-A5 Cells to Fluid Shear. JOURNAL OF BONE AND MINERAL RESEARCH, Vol. 23 (pp S147-S147)
- The role of mechanotransduction in bone tissue engineering. European Cells and Materials, Vol. 16(SUPPL. 3) (pp 84)
- Mechanobiology in bone tissue engineering: responses to fluid flow. TISSUE ENGINEERING PART A, Vol. 14(5) (pp 878-878)
- Human hair follicle dermal cells activate NF-魏B in response to TNF-伪 and IL-1尾 but are lipopolysaccharide tolerant. JOURNAL OF INVESTIGATIVE DERMATOLOGY, Vol. 128 (pp S149-S149)
- Use of aligned polymer microfibres for peripheral nerve repair. TISSUE ENGINEERING, Vol. 13(7) (pp 1774-1774)
- Development of biocompatible, biodegradable electrospun scaffolds for tissue engineering of human skin. TISSUE ENGINEERING, Vol. 13(7) (pp 1670-1671)
- Highly branched polymers via RAFT: Chain-end functionalization with peptides. ABSTRACTS OF PAPERS OF THE AMERICAN CHEMICAL SOCIETY, Vol. 230 (pp U3645-U3646)
- . Experimental Dermatology, Vol. 13(9) (pp 576-576)
- Sodium salicylate inhibits inflammation induced invasion and migration of human melanoma cells. BRITISH JOURNAL OF CANCER, Vol. 91 (pp S71-S71)
- Detection of protein kinase activity using a versatile streptavidin coated biotin capture membrane. MOLECULAR BIOLOGY OF THE CELL, Vol. 7 (pp 2110-2110)
- In vitro differentiation in a human cortical neuronal cell line (HCN-1A): Ultrastructure and immunocytochemistry. Proceedings Annual Meeting Microscopy Society of America (pp 40-41)
- . Regulatory Peptides, Vol. 37(3) (pp 331-331)
Preprints
- , openRxiv.
- Professional activities and memberships
-
- Emeritus Professor (January 2026)
- Head of Materials Science & Engineering, 爆料TV (2019 - 2021)
- Engineering Faculty Director of Research & Innovation (2016 - 2019)
- EPSRC CDT Advanced Biomedical Materials Co-director (Manchester-Sheffield) (2019-28)
- UKRI Future Leaders Fellowships Panel (2018 鈥 2021)
- Government of Ireland Panel Member (2018 鈥 2021)
- EPSRC UKCCSRC Board Member (2017 鈥 2020)
- Chair and Scientific Adviser - Versus Arthritis UK Centre for Tissue Engineering & Regenerative Medicine (Cambridge University) 2017 - 2021
- BBSRC Core Panel C and TRDF panel (2014 - 20)
- UK Tissue and Cell Engineering Society Board (2009 - 2021)
- Chair 鈥 Technicians Commitment for the 爆料TV
- External RAE Panel assessor 鈥 National University of Ireland (2018 鈥 2021)
- Executive Board of TERMIS-EU (2013-16)
- Member of EPSRC Peer Review College (2010-17)
- Academy of Finland Panel member (2015-18)
- Canada Foundation for Innovation panel member (2015)
- Editor of 鈥楳ethods in Molecular Biology鈥 book on 3D Cell Culture (Springer, USA, 2011)
- Editor of 鈥楥ellular In Vitro Testing鈥 book (PanStanford, Singapore, 2014)
- Patents
- Basnett P, Baz谩n Go帽i X, Claeyssens F, D铆ez Ahedo R, Glen A, Gonz谩lez P茅rez Francisco J, Haycock JW, Lukasiewicz B, Mendibil Blasco X, Merino 脕lvarez S, M谩rquez Posadas Mar铆a Del C, Nigmatullin R, Quintana Fern谩ndez I, Rodr铆guez Mu帽oz Francisco J, Roy I, Sherborne C, Taylor C. Implantable Nerve Guidance Conduit for Nerve Repair (2019). Priorities: EP2018054984W路2018-02-28. Application: EP2018054984W路2018-02-28. Publication: WO2019166087A1路2019-09-06.
- Crawford A, Buttle D, Haycock JW (2017) Medical Implant. Priorities: GB201513097A路2015-07-24. Application: GB2016052270W路2016-07-25. Publication: WO2017017425A1路2017-02-02.
- Botchway SW, Haycock J, Weinstein JA, Williams JAG. (2008) Imaging Techniques Using A Tridentate Ligand. Priorities: GB0818151A路2008-10-03; GB2009002369W路2009-10-05. Application: US200913122361A路2009-10-05. Publication: US2011262897A1路2011-10-27
- Haycock J, Hunter C, MacNeil S, Ryan T, Short R, Williams N (2002). Biomaterials Comprising a Melanocyte Stimulating Hormone (伪-MSH), and method of forming. Priorities: EP2018054984W路2018-02-28. Application: EP2018054984W路2018-02-28. Publication: WO2019166087A1路2019-09-06.